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ODSMT (O-Desmethyltramadol) is a synthetic opioid analgesic and the primary active metabolite of tramadol, a widely used prescription painkiller. It is chemically derived by removing a methyl group from tramadol, resulting in a compound with more potent opioid effects.

Chemical Properties

• IUPAC Name: (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
• Molecular Formula: C13H19NO2C_{13}H_{19}NO_2C13​H19​NO2​
• Class:
  • Opioid analgesic
  • Central nervous system (CNS) depressant
• Potency: O-DSMT is significantly stronger as an opioid receptor agonist compared to tramadol, primarily due to its higher affinity for mu-opioid receptors (MORs).

Mechanism of Action

O-DSMT exerts its effects primarily through two mechanisms:

1. Mu-Opioid Receptor Agonism:
   • Binds to MORs in the brain and spinal cord, producing analgesia, euphoria, and sedation.
2. Serotonin and Norepinephrine Reuptake Inhibition (SRI/NRI):
   • Similar to tramadol, O-DSMT can modulate neurotransmitters, contributing to its effects on mood and pain.

The combination of opioid activity and serotonin/norepinephrine reuptake inhibition makes it unique compared to other opioids. Buy ODSMT 

Effects

Physical Effects:

• Pain relief (analgesia)
• Sedation
• Respiratory depression (dose-dependent)
• Physical relaxation

Cognitive Effects:

• Euphoria
• Reduced anxiety
• Impaired cognitive function (at higher doses)

Side Effects:

• Drowsiness
• Nausea or vomiting
• Constipation
• Potential for dependence and addiction

Dosage and Duration

• Effective Dose: Typically ranges from 10–50 mg, depending on tolerance and individual sensitivity.
• Onset of Effects: 15–45 minutes (oral ingestion).
• Duration:
  • Effects last 4–6 hours, with residual sedation up to 8 hours. Buy ODSMT

Uses

1. Medical:
   • While ODSMT itself is not widely approved for medical use, it is a metabolite of tramadol, which is prescribed for moderate to severe pain.
2. Recreational:
   • Due to its euphoric effects, ODSMT is sometimes misused recreationally, though less commonly than other opioids like oxycodone or heroin.

Safety and Risks

Risks:

• Addiction and Dependence: ODSMT, like other opioids, has a high risk of addiction.
• Overdose: Can lead to fatal respiratory depression, especially when combined with other CNS depressants (e.g., alcohol or benzodiazepines).
• Serotonin Syndrome: The SRI effects pose a risk when combined with other serotonergic drugs like SSRIs or MDMA.

Harm Reduction Tips:

• Avoid combining with depressants or serotonergic substances.
• Start with a low dose to assess tolerance.
• Ensure the substance’s purity if obtained from non-medical sources.

Legality

• Global Status: ODSMT is not as widely regulated as other opioids but falls under analog laws in some countries, meaning its legality depends on its intended use.
• Availability: Commonly found as a research chemical in certain regions, but its sale and distribution are often restricted or monitored.

Comparison with Tramadol

Welcome to Research Trade Lab,  your trusted source for premium O-DSMT, a popular research chemical known for its unique properties. Explore the benefits of O-DSMT and its potential applications in research and scientific studies.

Discover O-DSMT:
O-DSMT, also known as O-Desmethyltramadol, is a synthetic opioid compound derived from tramadol. It exhibits analgesic properties and is often used in laboratory settings for research purposes. O-DSMT interacts with opioid receptors in the central nervous system, producing effects similar to other opioids.

Key Features and Characteristics of odsmt

• Pain Relief: This product is a potent analgesic that can provide relief from moderate to severe pain. It exerts its analgesic effects by binding to the mu-opioid receptors in the central nervous system, thereby reducing the perception of pain.
• Opioid Activity:  This product exhibits opioid-like activity due to its structural similarity to tramadol. It acts as a mu-opioid receptor agonist, which results in pain relief, sedation, and euphoria.
• Metabolism:  This product is a metabolite of tramadol. Tramadol is metabolized in the liver by the enzyme CYP2D6 to form ODSMT. This metabolite has a longer half-life than tramadol, leading to prolonged effects.
• Research Chemical: This product is frequently used as a research chemical. Researchers study its pharmacological properties, potential therapeutic applications, and its effects on opioid receptors and pain pathways.
• Dosage: The suggested dosage of this product is 1mg. However, it is crucial to note that dosages should be determined by researchers based on their specific experimental requirements and in compliance with legal and ethical guidelines.
• Storage:  This product should be stored in a cool, dry place, away from direct sunlight, moisture, and heat. The substance should be securely stored to prevent unauthorized access. Ordering Information:
  To inquire about pricing, and availability, or to place an order for ODSMT 1mg Pellets or any other research chemicals, please visit our website or contact our customer support team. Our dedicated team is available to assist you with any questions or concerns you may have.

Conclusion

ODSMT is a potent synthetic opioid derived from tramadol with enhanced analgesic and euphoric effects. While it offers unique dual-action mechanisms, it carries significant risks for addiction, overdose, and serotonin syndrome. Its use is primarily limited to research or recreational contexts, with increasing scrutiny due to its opioid nature.

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